BNF Publications

Update for Valproic Acid in BNF and BNF for Children

The following sections in the Valproic acid monograph in BNF Publications will be updated for the next print edition/digital update to bring the content in line with the Sodium valproate monograph. The content will be updated in BNF 72 (September 2016) and BNF for Children 2016-2017. Digital versions will be updated at the next scheduled release date – April 2016.

The updated content will read as follows:

Contra-indications: Acute porphyrias p.864; personal or familial history of severe hepatic dysfunction; known or suspected mitochondrial disorders (higher rate of acute liver failure and liver-related deaths)

Breastfeeding: Present in milk – risk of haematological disorders in breast-fed newborns and infants

A downloadable version of this update can be found here:

Update to Valproic acid monograph